Searchable abstracts of presentations at key conferences in endocrinology

ea0026p704 | Diabetes complications | ECE2011

Beta estrogen receptors inhibition improves wound healing in diabetes

Botusan I R , Sunkari V G , Grunler J , Lindberg S , Savu O , Steffensen K , Brismar K , Catrina S B

Diabetic wounds represent a medical and economical burden with a high need to develop more efficient therapies.Estrogens have a positive effect on cutaneous wound healing. Their decreased levels could count for impaired wound healing in elderly. The biological estrogen’s effects are mediated by two nuclear receptors subtypes (ERα and ERβ) and they were differently implied for the wound healing benefic processes. However, the estrogen effec...